Background:To our knowledge, no study assessed the association between dietary patterns and nasopharyngeal carcinoma (NPC) in low-incidence areas.Methods:We examined this association in a hospital-based case-control study carried out in Italy between 1992 and 2008, including 198 incident NPC cases and 594 controls. A posteriori dietary patterns were identified through principal component factor analysis performed on 28 nutrients and minerals derived from a 78-item food-frequency questionnaire. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using unconditional multiple logistic regression models on tertiles of factor scores.Results:We identified five dietary patterns named Animal products, Starch-rich, Vitamins and fibre, Animal unsaturated fatty acids (AUFAs), and Vegetable unsaturated fatty acids (VUFAs). The Animal product (OR=2.62, 95% CI=1.67-4.13, for the highest vs lowest score tertile), Starch-rich (OR=2.05, 95% CI=1.27-3.33), and VUFA (OR=1.90, 95% CI=1.22-2.96) patterns were positively associated with NPC. The AUFA pattern showed a positive association of borderline significance, whereas the Vitamins and fibre pattern was nonsignificantly but inversely associated with NPC.Conclusions:These findings suggest that diets rich in animal products, starch, and fats are positively related to NPC risk in this low-incidence country.
Edefonti, V., Nicolussi, F., Polesel, J., Bravi, F., Bosetti, C., Garavello, W., et al. (2015). Nutrient-based dietary patterns and nasopharyngeal cancer: Evidence from an exploratory factor analysis. BRITISH JOURNAL OF CANCER, 112(3), 446-454.
|Citazione:||Edefonti, V., Nicolussi, F., Polesel, J., Bravi, F., Bosetti, C., Garavello, W., et al. (2015). Nutrient-based dietary patterns and nasopharyngeal cancer: Evidence from an exploratory factor analysis. BRITISH JOURNAL OF CANCER, 112(3), 446-454.|
|Tipo:||Articolo in rivista - Articolo scientifico|
|Carattere della pubblicazione:||Scientifica|
|Presenza di un coautore afferente ad Istituzioni straniere:||No|
|Titolo:||Nutrient-based dietary patterns and nasopharyngeal cancer: Evidence from an exploratory factor analysis|
|Autori:||Edefonti, V; Nicolussi, F; Polesel, J; Bravi, F; Bosetti, C; Garavello, W; La Vecchia, C; Bidoli, E; Decarli, A; Serraino, D; Calza, S; Ferraroni, M|
NICOLUSSI, FEDERICA (Secondo)
|Data di pubblicazione:||2015|
|Rivista:||BRITISH JOURNAL OF CANCER|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1038/bjc.2014.611|
|Appare nelle tipologie:||01 - Articolo su rivista|