Manifestazioni orali tipiche nel paziente neutropenico

Leucopenia is a disease caused by a reduction of circulating leukocytes. Leucopenia may be caused by alterations of extrinsic factors of myeloid line cell or by intrinsic alterations of cell growth line. Systemic symptoms are directly related to PMNs blood level. Clinical manifestations are related to bacterial infections. The dentist's role in diagnosis is important, since oral signs and symptoms may be the first to appear. Oral signs of neutropenia include ulcers, periodontal disease and opportunistic infection. Therapy should aim to prevent and control opportunistic infections.