T-lymphocyte subsets, using the monoclonal antibodies OKT3 (peripheral T-cells), OKT4 (helper/inducer T-cells) and OKT8 (suppressor/cytotoxic T-cells) were measured in peripheral blood from 110 patients with various forms of primary and secondary glomerulonephritis (GN) (Berger's disease, membranous GN, focal glomerulosclerosis, membranoproliferative GN, lupus nephritis and mixed essential cryoglobulinaemia with GN). We have found a significantly higher OKT4+/OKT8+ ratio in patients with Berger's disease and membranous GN and a rather low OKT4+/OKT8+ ratio in patients with lupus nephritis and mixed essential cryoglobulinaemia, due to a significant decrease in OKT4+ cells. Our results suggest an imbalance in immunoregulatory mechanisms in some forms of GN
Fornasieri, A., Sinico, R., Fiorini, G., Goldaniga, D., Colasanti, G., Vendemia, F., et al. (1983). T-lymphocyte subsets in primary and secondary glomerulonephritis. PROCEEDINGS OF THE EUROPEAN DIALYSIS AND TRANSPLANT ASSOCIATION, 19, 635-641.
Citazione: | Fornasieri, A., Sinico, R., Fiorini, G., Goldaniga, D., Colasanti, G., Vendemia, F., et al. (1983). T-lymphocyte subsets in primary and secondary glomerulonephritis. PROCEEDINGS OF THE EUROPEAN DIALYSIS AND TRANSPLANT ASSOCIATION, 19, 635-641. |
Tipo: | Articolo in rivista - Articolo scientifico |
Carattere della pubblicazione: | Scientifica |
Presenza di un coautore afferente ad Istituzioni straniere: | No |
Titolo: | T-lymphocyte subsets in primary and secondary glomerulonephritis |
Autori: | Fornasieri, A; Sinico, R; Fiorini, G; Goldaniga, D; Colasanti, G; Vendemia, F; Gibelli, A; D'Amico, G |
Autori: | SINICO, RENATO ALBERTO (Secondo) |
Data di pubblicazione: | 1983 |
Lingua: | English |
Rivista: | PROCEEDINGS OF THE EUROPEAN DIALYSIS AND TRANSPLANT ASSOCIATION |
Appare nelle tipologie: | 01 - Articolo su rivista |