Shared idiotype specificities (CRIs) among monoclonal IgM rheumatoid factors from patients with essential mixed cryoglobulinemia have been demonstrated with the use of polyclonal antisera and have been confirmed, more recently, using monoclonal antibodies. In this paper we will summarize some of the work that has been performed in our laboratory using anti-idiotypic monoclonal antibodies. Such reagents allowed us to detect CRIs on cryoprecipitable rheumatoid factors, to detect idiotype-positive cells in bone marrow and peripheral blood, and to identify glomerular immune deposits
Sinico, R., Fornasieri, A., Indaco, A., Radice, A., Bernasconi, P., Gibelli, A., et al. (1995). Cross-reactive idiotypes on cryoprecipitating monoclonal IgMk rheumatoid factors. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 13(Suppl 13), S105-S107.
Citazione: | Sinico, R., Fornasieri, A., Indaco, A., Radice, A., Bernasconi, P., Gibelli, A., et al. (1995). Cross-reactive idiotypes on cryoprecipitating monoclonal IgMk rheumatoid factors. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 13(Suppl 13), S105-S107. |
Tipo: | Articolo in rivista - Articolo scientifico |
Carattere della pubblicazione: | Scientifica |
Presenza di un coautore afferente ad Istituzioni straniere: | No |
Titolo: | Cross-reactive idiotypes on cryoprecipitating monoclonal IgMk rheumatoid factors |
Autori: | Sinico, R; Fornasieri, A; Indaco, A; Radice, A; Bernasconi, P; Gibelli, A; D'Amico, G |
Autori: | SINICO, RENATO ALBERTO (Primo) |
Data di pubblicazione: | 1995 |
Lingua: | English |
Rivista: | CLINICAL AND EXPERIMENTAL RHEUMATOLOGY |
Appare nelle tipologie: | 01 - Articolo su rivista |