It was reported by several groups that patients diagnosed as primary antiphospholipid syndrome (PAPS) had developed a full-blown systemic lupus erythematosus (SLE) even after many years of follow-up. Little is known about clinical and/or serological factors that may help predict such evolution. Antinucleosome antibodies (anti-NCS) were described to appear in early stages of SLE, in particular before anti-dsDNA antibodies. The aim of the study is to evaluate the prevalence of anti-NCS in a large cohort of PAPS patients

Andreoli, L., Pregnolato, F., Burlingame, R., Fanelli, V., Allegri, F., Radice, A., et al. (2008). [Primary antiphospholipid syndrome evolving into systemic lupus erythematosus: may antinucleosome antibodies be predictive?]. REUMATISMO, 60(3), 185-191.

[Primary antiphospholipid syndrome evolving into systemic lupus erythematosus: may antinucleosome antibodies be predictive?]

SINICO, RENATO ALBERTO;
2008

Abstract

It was reported by several groups that patients diagnosed as primary antiphospholipid syndrome (PAPS) had developed a full-blown systemic lupus erythematosus (SLE) even after many years of follow-up. Little is known about clinical and/or serological factors that may help predict such evolution. Antinucleosome antibodies (anti-NCS) were described to appear in early stages of SLE, in particular before anti-dsDNA antibodies. The aim of the study is to evaluate the prevalence of anti-NCS in a large cohort of PAPS patients
Articolo in rivista - Articolo scientifico
Adult; Antibodies, Antinuclear; Antibody Specificity; Antiphospholipid Syndrome; Autoantigens; DNA; Disease Progression; Female; Follow-Up Studies; Humans; Immunoglobulin G; Immunoglobulin M; Lupus Erythematosus, Systemic; Male; Nucleosomes; Prognosis
Italian
185
191
7
Andreoli, L., Pregnolato, F., Burlingame, R., Fanelli, V., Allegri, F., Radice, A., et al. (2008). [Primary antiphospholipid syndrome evolving into systemic lupus erythematosus: may antinucleosome antibodies be predictive?]. REUMATISMO, 60(3), 185-191.
Andreoli, L; Pregnolato, F; Burlingame, R; Fanelli, V; Allegri, F; Radice, A; Corace, C; Sinico, R; Tincani, A; Meroni, P
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/139372
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