We report here the accidental finding of a transient central pontine myelinolysis (CPM)-like brain lesion in an asymptomatic diffuse large B cell lymphoma patient. We could not find any significant electrolyte disturbance and we think as unlikely any drug-related effect. Besides simple casual association, we may conclude suggesting an interesting hypothesis: the lymphoma per se might predispose to minor CPM-like events, perhaps due to the activation of mediators (e.g., cytokines) that in the classical osmotic demyelination syndrome are usually operating downstream, following the initial well-known rapid osmotic changes

Doni, E., Tremolizzo, L., Patassini, M., Pioltelli, P., Ferrarese, C., Appollonio, I. (2016). Asymptomatic central pontine myelinolysis without hyponatriemia in diffuse large B cell lymphoma. NEUROLOGICAL SCIENCES, 37(12), 2035-2037 [10.1007/s10072-016-2689-4].

Asymptomatic central pontine myelinolysis without hyponatriemia in diffuse large B cell lymphoma

DONI, ELISA
Primo
;
TREMOLIZZO, LUCIO
Secondo
;
PIOLTELLI, PIETRO ENRICO;FERRARESE, CARLO
Penultimo
;
APPOLLONIO, ILDEBRANDO
Ultimo
2016

Abstract

We report here the accidental finding of a transient central pontine myelinolysis (CPM)-like brain lesion in an asymptomatic diffuse large B cell lymphoma patient. We could not find any significant electrolyte disturbance and we think as unlikely any drug-related effect. Besides simple casual association, we may conclude suggesting an interesting hypothesis: the lymphoma per se might predispose to minor CPM-like events, perhaps due to the activation of mediators (e.g., cytokines) that in the classical osmotic demyelination syndrome are usually operating downstream, following the initial well-known rapid osmotic changes
Articolo in rivista - Articolo scientifico
Asymptomatic; Brain MR; Central pontine myelinolysis; DLBCL; Lymphoma; Osmotic demyelination syndrome;
Asymptomatic; Brain MR; Central pontine myelinolysis; DLBCL; Lymphoma; Osmotic demyelination syndrome; Medicine (all); 2708; Neurology (clinical); Psychiatry and Mental Health
English
3-ago-2016
2016
37
12
2035
2037
none
Doni, E., Tremolizzo, L., Patassini, M., Pioltelli, P., Ferrarese, C., Appollonio, I. (2016). Asymptomatic central pontine myelinolysis without hyponatriemia in diffuse large B cell lymphoma. NEUROLOGICAL SCIENCES, 37(12), 2035-2037 [10.1007/s10072-016-2689-4].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/139032
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