Pityriasis rosea is an acute, self-healing exanthem characterized by oval erythematous-squamous lesions of the trunk and limbs, that usually spares face, scalp, palms, and soles. Constitutional symptoms, which have the character of true prodromes; clinical features, which resemble those of the known exanthems; and many epidemiologic data all suggest an infectious origin. A host of infectious agents have been incriminated, but, recently, human herpesvirus 6 and 7 have been extensively studied. The goal of this review is to outline the epidemiologic, clinical, histologic, and ultrastructural features of pityriasis rosea, but mainly to stress its possible human herpesvirus nature. In addition, clues have been added to help the reader to go through the complex subtleties of the virologic investigation. © 2008 American Academy of Dermatology, Inc.

Drago, F., Broccolo, F., Rebora, A. (2009). Pityriasis rosea: An update with a critical appraisal of its possible herpesviral etiology. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 61(2), 303-318 [10.1016/j.jaad.2008.07.045].

Pityriasis rosea: An update with a critical appraisal of its possible herpesviral etiology

BROCCOLO, FRANCESCO
Secondo
;
2009

Abstract

Pityriasis rosea is an acute, self-healing exanthem characterized by oval erythematous-squamous lesions of the trunk and limbs, that usually spares face, scalp, palms, and soles. Constitutional symptoms, which have the character of true prodromes; clinical features, which resemble those of the known exanthems; and many epidemiologic data all suggest an infectious origin. A host of infectious agents have been incriminated, but, recently, human herpesvirus 6 and 7 have been extensively studied. The goal of this review is to outline the epidemiologic, clinical, histologic, and ultrastructural features of pityriasis rosea, but mainly to stress its possible human herpesvirus nature. In addition, clues have been added to help the reader to go through the complex subtleties of the virologic investigation. © 2008 American Academy of Dermatology, Inc.
Articolo in rivista - Articolo scientifico
Adult; Age Distribution; Female; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; In Situ Hybridization; Incidence; Male; Middle Aged; Pityriasis Rosea; Polymerase Chain Reaction; Prognosis; RNA, Viral; Remission, Spontaneous; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Sex Distribution; Skin Diseases, Viral; Young Adult; 2708
English
303
318
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Drago, F., Broccolo, F., Rebora, A. (2009). Pityriasis rosea: An update with a critical appraisal of its possible herpesviral etiology. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 61(2), 303-318 [10.1016/j.jaad.2008.07.045].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/136576
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