Pityriasis rosea is an acute exanthem with many clinical and epidemiologic features of an infectious disease. To date, human herpesvirus (HHV)-6 and HHV-7 appear to be the most indicted culprits, and the evidence in favor of this hypothesis and the controversial results produced elsewhere are discussed. The complex pathophysiology of HHV-6 and HHV-7 infection, their diffusion in the population at large, the difficulties of understanding whether the infection is still latent or is clinically manifest, and well as whether pityriasis rosea depends on a reinfection or on a viral reactivation, all make the issue extremely difficult to study and understand
Rebora, A., Drago, F., Broccolo, F. (2010). Pityriasis rosea and herpesviruses: Facts and controversies. CLINICS IN DERMATOLOGY, 28(5), 497-501 [10.1016/j.clindermatol.2010.03.005].
Pityriasis rosea and herpesviruses: Facts and controversies
BROCCOLO, FRANCESCOUltimo
2010
Abstract
Pityriasis rosea is an acute exanthem with many clinical and epidemiologic features of an infectious disease. To date, human herpesvirus (HHV)-6 and HHV-7 appear to be the most indicted culprits, and the evidence in favor of this hypothesis and the controversial results produced elsewhere are discussed. The complex pathophysiology of HHV-6 and HHV-7 infection, their diffusion in the population at large, the difficulties of understanding whether the infection is still latent or is clinically manifest, and well as whether pityriasis rosea depends on a reinfection or on a viral reactivation, all make the issue extremely difficult to study and understandI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.