Tissue engineering relies on the possibility to engineer cell microenvironments by means of bioactive materials, biochemical and physical stimuli in order to guide cell behaviour and to regenerate damaged tissue. Despite the relevance of glycan epitopes as signaling molecules, and the recent advances in glycomics, their use as biomolecular cues at the interface between materials and cells for the controlled stimulation of adhesion and differentiation processes for regenerative medicine applications is still limited. In this concept article we will briefly outline the basis and the impact on health and economics of regenerative medicine, together with the recent applications of the glycocode in tissue regeneration approaches.

Russo, L., Cipolla, L. (2016). Glycomics: New Challenges and Opportunities in Regenerative Medicine. CHEMISTRY-A EUROPEAN JOURNAL, 22(38), 13380-13388 [10.1002/chem.201602156].

Glycomics: New Challenges and Opportunities in Regenerative Medicine

RUSSO, LAURA
Primo
;
CIPOLLA, LAURA FRANCESCA
2016

Abstract

Tissue engineering relies on the possibility to engineer cell microenvironments by means of bioactive materials, biochemical and physical stimuli in order to guide cell behaviour and to regenerate damaged tissue. Despite the relevance of glycan epitopes as signaling molecules, and the recent advances in glycomics, their use as biomolecular cues at the interface between materials and cells for the controlled stimulation of adhesion and differentiation processes for regenerative medicine applications is still limited. In this concept article we will briefly outline the basis and the impact on health and economics of regenerative medicine, together with the recent applications of the glycocode in tissue regeneration approaches.
Articolo in rivista - Review Essay
biomaterials; carbohydrates; extracellular matrix; glycoscience; regenerative medicine;
biomaterials; carbohydrates; extracellular matrix; glycoscience; regenerative medicine; Chemistry (all)
English
13380
13388
9
Russo, L., Cipolla, L. (2016). Glycomics: New Challenges and Opportunities in Regenerative Medicine. CHEMISTRY-A EUROPEAN JOURNAL, 22(38), 13380-13388 [10.1002/chem.201602156].
Russo, L; Cipolla, L
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/135145
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