Disease, trauma, and aging account for a significant number of clinical disorders. Regenerative medicine is emerging as a very promising therapeutic option. The design and development of new cell-customised biomaterials able to mimic extracellular matrix (ECM) functionalities represents one of the major strategies to control the cell fate and stimulate tissue regeneration. Recently, hydrogels have received a considerable interest for their use in the modulation and control of cell fate during the regeneration processes. Several synthetic bioresponsive hydrogels are being developed in order to facilitate cell-matrix and cell-cell interactions. In this review, new strategies and future perspectives of such synthetic cell microenvironments will be highlighted

Sgambato, A., Cipolla, L., Russo, L. (2016). Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering. GELS, 2(4) [10.3390/gels2040028].

Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering

SGAMBATO, ANTONELLA
Primo
;
CIPOLLA, LAURA FRANCESCA
Secondo
;
RUSSO, LAURA
Ultimo
2016

Abstract

Disease, trauma, and aging account for a significant number of clinical disorders. Regenerative medicine is emerging as a very promising therapeutic option. The design and development of new cell-customised biomaterials able to mimic extracellular matrix (ECM) functionalities represents one of the major strategies to control the cell fate and stimulate tissue regeneration. Recently, hydrogels have received a considerable interest for their use in the modulation and control of cell fate during the regeneration processes. Several synthetic bioresponsive hydrogels are being developed in order to facilitate cell-matrix and cell-cell interactions. In this review, new strategies and future perspectives of such synthetic cell microenvironments will be highlighted
Articolo in rivista - Review Essay
hydrogels, ECM, regenerative medicine
English
Sgambato, A., Cipolla, L., Russo, L. (2016). Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering. GELS, 2(4) [10.3390/gels2040028].
Sgambato, A; Cipolla, L; Russo, L
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/135142
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