The endogenous reactivation of HHV-6/7 may result in Pityriasis rosea (PR). The blood viral load distinguishes between latent and clinically manifest disease. We compared HHV-7/6 DNA load in saliva and blood samples of PR patients and controls. Salivary PCR assay is inadequate to detect and follow-up HHV-7 reactivation in PR. Only the plasma viral DNA load remains the direct marker of the viral replication.

Broccolo, F., Ciccarese, G., Oggioni, M., Rebora, A., Parodi, A., Drago, F. (2014). The saliva quantitative PCR assay is inadequate to detect and monitor human herpesvirus-7 and -6 reactivation in patients with Pityriasis rosea. JOURNAL OF CLINICAL VIROLOGY, 61(4), 615-616 [10.1016/j.jcv.2014.09.020].

The saliva quantitative PCR assay is inadequate to detect and monitor human herpesvirus-7 and -6 reactivation in patients with Pityriasis rosea

BROCCOLO, FRANCESCO
;
2014

Abstract

The endogenous reactivation of HHV-6/7 may result in Pityriasis rosea (PR). The blood viral load distinguishes between latent and clinically manifest disease. We compared HHV-7/6 DNA load in saliva and blood samples of PR patients and controls. Salivary PCR assay is inadequate to detect and follow-up HHV-7 reactivation in PR. Only the plasma viral DNA load remains the direct marker of the viral replication.
Articolo in rivista - Articolo scientifico
Herpesviruses; HHV-6; HHV-7; Plasma viremia; Reactivation; Saliva; Adolescent; Adult; DNA, Viral; Female; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Male; Pityriasis Rosea; Plasma; Real-Time Polymerase Chain Reaction; Saliva; Viral Load; Young Adult; Virus Activation; Virology; Infectious Diseases; Medicine (all)
English
615
616
2
Broccolo, F., Ciccarese, G., Oggioni, M., Rebora, A., Parodi, A., Drago, F. (2014). The saliva quantitative PCR assay is inadequate to detect and monitor human herpesvirus-7 and -6 reactivation in patients with Pityriasis rosea. JOURNAL OF CLINICAL VIROLOGY, 61(4), 615-616 [10.1016/j.jcv.2014.09.020].
Broccolo, F; Ciccarese, G; Oggioni, M; Rebora, A; Parodi, A; Drago, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/135088
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