Definition of white coat hypertension (WCH) traditionally relies on elevated office blood pressure (BP) during repeated visits concomitant with normal out-of-office BP values, as assessed by home and/or 24-h ambulatory BP monitoring measurements. Accumulating evidence focusing on the association of WCH with target organ damage and, more importantly, with cardiovascular events indicates that the risk conveyed by this condition is intermediate between normotension and sustained hypertension. This article will review a number of issues concerning WCH with particular emphasis on the following: (1) prevalence and clinical correlates, (2) association with target organ damage and cardiovascular events, (3) therapeutic interventions. Data will refer to the original WCH definition, based on out-of-office BP determined by 24-h ambulatory BP monitoring; at variance from home BP measurement, this approach rules out the potentially confounding effect of a clinically relevant abnormal BP phenotype such as isolated nocturnal hypertension.

Cuspidi, C., Sala, C., Grassi, G., Mancia, G. (2016). White Coat Hypertension: to Treat or Not to Treat?. CURRENT HYPERTENSION REPORTS, 18(11) [10.1007/s11906-016-0687-9].

White Coat Hypertension: to Treat or Not to Treat?

CUSPIDI, CESARE
Primo
;
GRASSI, GUIDO
Penultimo
;
MANCIA, GIUSEPPE
Ultimo
2016

Abstract

Definition of white coat hypertension (WCH) traditionally relies on elevated office blood pressure (BP) during repeated visits concomitant with normal out-of-office BP values, as assessed by home and/or 24-h ambulatory BP monitoring measurements. Accumulating evidence focusing on the association of WCH with target organ damage and, more importantly, with cardiovascular events indicates that the risk conveyed by this condition is intermediate between normotension and sustained hypertension. This article will review a number of issues concerning WCH with particular emphasis on the following: (1) prevalence and clinical correlates, (2) association with target organ damage and cardiovascular events, (3) therapeutic interventions. Data will refer to the original WCH definition, based on out-of-office BP determined by 24-h ambulatory BP monitoring; at variance from home BP measurement, this approach rules out the potentially confounding effect of a clinically relevant abnormal BP phenotype such as isolated nocturnal hypertension.
Articolo in rivista - Articolo scientifico
Cardiovascular prognosis; Organ damage; Treatment; White coat hypertension;
White coat hypertension; Organ damage; Cardiovascular prognosis; Treatment
English
Cuspidi, C., Sala, C., Grassi, G., Mancia, G. (2016). White Coat Hypertension: to Treat or Not to Treat?. CURRENT HYPERTENSION REPORTS, 18(11) [10.1007/s11906-016-0687-9].
Cuspidi, C; Sala, C; Grassi, G; Mancia, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/134447
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