The mucosal immune system is the first line of defence against bacterial and viral infections and is crucial in maintaining mucosal homeostasis. In the gut, mucosal dendritic cells offer an alternative pathway to epithelial cells for antigen uptake, to initiate antigen-specific immune responses. It has recently been shown that lamina propria dendritic cells of the small intestine actively sample gut bacteria through the formation of transepithelial dendrites by a mechanism that is dependent on the expression of the chemokine receptor CX3CR1.

Foti, M., Castagnoli, P. (2005). Antigen sampling by mucosal dendritic cells. TRENDS IN MOLECULAR MEDICINE, 11(9), 394-396 [10.1016/j.molmed.2005.07.001].

Antigen sampling by mucosal dendritic cells

FOTI, MARIA;CASTAGNOLI, PAOLA
2005

Abstract

The mucosal immune system is the first line of defence against bacterial and viral infections and is crucial in maintaining mucosal homeostasis. In the gut, mucosal dendritic cells offer an alternative pathway to epithelial cells for antigen uptake, to initiate antigen-specific immune responses. It has recently been shown that lamina propria dendritic cells of the small intestine actively sample gut bacteria through the formation of transepithelial dendrites by a mechanism that is dependent on the expression of the chemokine receptor CX3CR1.
Articolo in rivista - Articolo scientifico
Dendritic cells, mucosal immunity, gut immunology
English
set-2005
11
9
394
396
none
Foti, M., Castagnoli, P. (2005). Antigen sampling by mucosal dendritic cells. TRENDS IN MOLECULAR MEDICINE, 11(9), 394-396 [10.1016/j.molmed.2005.07.001].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/13279
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