An increasing amount of data suggests that systolic blood pressure (SBP) and pulse pressure (PP) may more closely relate to and thus favour the atherogenic process than does diastolic blood pressure (DBP), The baseline data from the ongoing European Lacidipine Study on Atherosclerosis (ELSA) recently indicated that carotid artery atherosclerosis in normocholesterolaemic patients with mild or moderate essential hypertension is more closely related to SBP and more so PP than to DBP and lipid variables, Other new data point to the effects of hypertension on arterial compliance, as well as the effects of 24-h blood pressure variability on arterial compliance and distensibility. When viewed in their entirety, these data present a compelling case for the closer monitoring of SBP and PP with respect to arterial compliance, and the need for aggressive blood pressure treatment to control and perhaps reverse the underlying pathological changes in arterial structure and function in hypertensive patients. J Hypertens 17 (suppl 5):S55-S61 (C) 1999 Lippincott Williams & Wilkins.

Mancia, G., Giannattasio, C., Failla, M., Sega, R., Parati, G. (1999). Systolic blood pressure and pulse pressure: Role of 24-h mean values and variability in the determination of organ damage. JOURNAL OF HYPERTENSION, 17, S55-S62.

Systolic blood pressure and pulse pressure: Role of 24-h mean values and variability in the determination of organ damage

MANCIA, GIUSEPPE;GIANNATTASIO, CRISTINA;SEGA, ROBERTO;PARATI, GIANFRANCO
1999

Abstract

An increasing amount of data suggests that systolic blood pressure (SBP) and pulse pressure (PP) may more closely relate to and thus favour the atherogenic process than does diastolic blood pressure (DBP), The baseline data from the ongoing European Lacidipine Study on Atherosclerosis (ELSA) recently indicated that carotid artery atherosclerosis in normocholesterolaemic patients with mild or moderate essential hypertension is more closely related to SBP and more so PP than to DBP and lipid variables, Other new data point to the effects of hypertension on arterial compliance, as well as the effects of 24-h blood pressure variability on arterial compliance and distensibility. When viewed in their entirety, these data present a compelling case for the closer monitoring of SBP and PP with respect to arterial compliance, and the need for aggressive blood pressure treatment to control and perhaps reverse the underlying pathological changes in arterial structure and function in hypertensive patients. J Hypertens 17 (suppl 5):S55-S61 (C) 1999 Lippincott Williams & Wilkins.
Articolo in rivista - Articolo scientifico
24-h blood pressure; arterial compliance; arterial distensibility; blood pressure variability; pulse pressure; systolic blood pressure
English
1999
17
S55
S62
none
Mancia, G., Giannattasio, C., Failla, M., Sega, R., Parati, G. (1999). Systolic blood pressure and pulse pressure: Role of 24-h mean values and variability in the determination of organ damage. JOURNAL OF HYPERTENSION, 17, S55-S62.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/12046
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