The research and development of personalized medical treatments is increasing steadily fostered by its large societal impact. The ability of non-spherical gold nanoparticles to locally and efficiently release heat when irradiated in Near Infrared (NIR) wavelength region is a promising tool for photothermal medical therapies. In the present work, stable inks containing PEGylated gold nanostars (GNS) were obtained and inkjet-printed on a pigment coated paper substrate. Significant photothermal effect of the printed patterns was observed under Near Infrared (NIR) excitation of the Localized Surface Plasmon Resonance (LSPR) of the GNS. These preliminary results support, in perspective, the application of printed GNS patterns for thermal medical treatments either by direct localized heating, or by temperature triggered drug release.
Borzenkov, M., Chirico, G., Collini, M., Määttänen, A., Ihalainen, P., Cabrini, E., et al. (2016). Photothermal effect of gold nanostars inkjet-printed on coated paper substrate under near-infrared irradiation. In Biophotonics: Photonic Solutions for Better Health Care V (Proceedings SPIE 9887). SPIE [10.1117/12.2229824].
Photothermal effect of gold nanostars inkjet-printed on coated paper substrate under near-infrared irradiation
BORZENKOV, MYKOLAPrimo
;CHIRICO, GIUSEPPE
Secondo
;COLLINI, MADDALENA;
2016
Abstract
The research and development of personalized medical treatments is increasing steadily fostered by its large societal impact. The ability of non-spherical gold nanoparticles to locally and efficiently release heat when irradiated in Near Infrared (NIR) wavelength region is a promising tool for photothermal medical therapies. In the present work, stable inks containing PEGylated gold nanostars (GNS) were obtained and inkjet-printed on a pigment coated paper substrate. Significant photothermal effect of the printed patterns was observed under Near Infrared (NIR) excitation of the Localized Surface Plasmon Resonance (LSPR) of the GNS. These preliminary results support, in perspective, the application of printed GNS patterns for thermal medical treatments either by direct localized heating, or by temperature triggered drug release.
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