The assessment of sodium sensitivity requires to measure the difference in mean arterial pressure (MAP) at the end of sodium-loading (SLoad) and sodium-depletion (SDepl) maneuvers with an arm-cuff manometer. Aim of this study is to evaluate whether MAP measuring devices based on the volume-clamp method at the finger can also be used for assessing sodium sensitivity. Sixty-eight normotensive volunteers underwent SLoad and SDepl diets in random order. MAP was simultaneously measured at the end of each diet with arm (Spacelabs 90207) and finger (Portapres model-2) cuff devices. The sodium sensitivity was assessed as the difference in MAP at the end of SLoad and SDepl diets (ΔMAP), and as salt-sensitivity index (SSI; SSI=ΔMAP divided by the difference in urinary-sodium-excretion rate at the end of the diets). Discrepancies between finger and arm-cuff devices in ΔMAP or SSI were evaluated by Bland and Altman analysis. Even if discrepancies between devices had null-fixed bias, results showed a significant proportional bias and large limits of agreement (between -25 and 25 mm Hg for ΔMAP, between -196 and 180 mm Hg mol-1 per day for SSI). The SSI distribution over the group was larger, flatter and less symmetric if derived from finger-cuff rather than arm-cuff devices, and this influenced substantially the identification of salt-sensitive individuals. Therefore, the response of MAP to SLoad/SDepl diets and consequently the assessment of the salt-sensitivity condition depends importantly on the measurement site, and brachial measures should be preferred for consistency with literature and normative data.
Castiglioni, P., Parati, G., Di Rienzo, M., Brambilla, V., Brambilla, L., Gualerzi, M., et al. (2015). Blood pressure changes after high- and low-salt diets: Are intermittent arm measures and beat-by-beat finger measures equivalent?. JOURNAL OF HUMAN HYPERTENSION, 29(7), 430-435.
|Citazione:||Castiglioni, P., Parati, G., Di Rienzo, M., Brambilla, V., Brambilla, L., Gualerzi, M., et al. (2015). Blood pressure changes after high- and low-salt diets: Are intermittent arm measures and beat-by-beat finger measures equivalent?. JOURNAL OF HUMAN HYPERTENSION, 29(7), 430-435.|
|Tipo:||Articolo in rivista - Articolo scientifico|
|Carattere della pubblicazione:||Scientifica|
|Presenza di un coautore afferente ad Istituzioni straniere:||No|
|Titolo:||Blood pressure changes after high- and low-salt diets: Are intermittent arm measures and beat-by-beat finger measures equivalent?|
|Autori:||Castiglioni, P; Parati, G; Di Rienzo, M; Brambilla, V; Brambilla, L; Gualerzi, M; Lazzeroni, D; Coruzzi, P|
PARATI, GIANFRANCO (Secondo) (Corresponding)
|Data di pubblicazione:||2015|
|Rivista:||JOURNAL OF HUMAN HYPERTENSION|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1038/jhh.2014.110|
|Appare nelle tipologie:||01 - Articolo su rivista|