Sfoglia per Autore
Dissection of the RET/ß-catenin interaction in the TPC1 thyroid cancer cell line
2011 Tartari, C; Donadoni, C; Manieri, E; Mologni, L; Mina, P; Villa, A; GAMBACORTI PASSERINI, C
Development of RET kinase inhibitors for targeted cancer therapy
2011 Mologni, L
Focal adhesion kinase (FAK) binds RET kinase via its FERM domain, priming a direct and reciprocal RET-FAK transactivation mechanism
2011 Plaza Menacho, I; Morandi, A; Mologni, L; Boender, P; GAMBACORTI PASSERINI, C; Magee, A; Hofstra, R; Knowles, P; Mcdonald, N; Isacke, C
Sphingosine kinase 1 overexpression is regulated by signaling through PI3K, AKT2, and mTOR in imatinib-resistant chronic myeloid leukemia cells
2011 Marfe, G; Di Stefano, C; Gambacurta, A; Ottone, T; Martini, V; Abruzzese, E; Mologni, L; Sinibaldi Salimei, P; de Fabritis, P; GAMBACORTI PASSERINI, C; Amadori, S; Birge, R
ERG deregulation induces PIM1 over-expression and aneuploidy in prostate epithelial cells
2011 Magistroni, V; Mologni, L; Sanselicio, S; Reid, J; Redaelli, S; Piazza, R; Viltadi, M; Bovo, G; Strada, G; Grasso, M; Gariboldi, M; GAMBACORTI PASSERINI, C
A New BCR-ABL1 Mutation (L248R) Is Highly Resistant to Imatinib, Bosutinib, Nilotinib and Dasatinib, but Can Be Inhibited by AP-24534 and DCC-2036
2010 Redaelli, S; Mologni, L; Rostagno, R; Piazza, R; Viltadi, M; Wise, S; Flynn, D; GAMBACORTI PASSERINI, C
Inhibitors of the RET tyrosine kinase based on a 2-(alkylsulfanyl)-4-(3- thienyl)nicotinonitrile scaffold
2010 Brandt, W; Mologni, L; Preu, L; Lemcke, T; Gambacorti-Passerini, C; Kunick, C
Synthesis, structure-activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors
2010 Mologni, L; Rostagno, R; Brussolo, S; Knowles, P; Kjaer, S; Murray Rust, J; Rosso, E; Zambon, A; Scapozza, L; Mcdonald, N; Lucchini, V; GAMBACORTI PASSERINI, C
Colorectal tumors are effectively eradicated by combined inhibition of {beta}-catenin, KRAS, and the oncogenic transcription factor ITF2
2010 Mologni, L; Dekhil, H; Ceccon, M; Purgante, S; Lan, C; Cleris, L; Magistroni, V; Formelli, F; GAMBACORTI PASSERINI, C
Role of TMPRSS2/ERG in cellular transformation
2009 Magistroni, V; Sanselicio, S; Mologni, L; Reid, J; Gariboldi, M; GAMBACORTI PASSERINI, C
Resistance Profile of the BCR/ABL Inhibitor Bosutinib Using a High Throughput random Mutagenesis Assay
2009 Piazza, R; Redaelli, S; Ceccon, M; Mogavero, A; Marega, M; Mologni, L; Boschelli, F; Pogliani, E; GAMBACORTI PASSERINI, C
Valproic acid enhances bosutinib cytotoxicity in colon cancer cells
2009 Mologni, L; Cleris, L; Magistroni, V; Piazza, R; Boschelli, F; Formelli, F; GAMBACORTI PASSERINI, C
Alfa-carboline inhibitors of npm-alk, ret, and bcr-abl
2008 GAMBACORTI PASSERINI, C; Mologni, L; Scapozza, L; Ahmed, S; Goekjian, P; Gueyrard, D; Popowycz, F; Joseph, B; Schneider, C; Garcia, P
Characterization of compound 584, an Abl kinase inhibitor with lasting effects
2008 Puttini, M; Redaelli, S; Moretti, L; Brussolo, S; Gunby, R; Mologni, L; Marchesi, E; Cleris, L; Donella deana, A; Drueckes, P; Sala, E; Lucchini, V; Kubbutat, M; Formelli, F; Zambon, A; Scapozza, L; GAMBACORTI PASSERINI, C
BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells
2008 Sala, E; Mologni, L; Truffa, S; Gaetano, C; Bollag, G; GAMBACORTI PASSERINI, C
Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation
2007 Coluccia, A; Vacca, A; Dunach, M; Mologni, L; Redaelli, S; Bustos, V; Benati, D; Pinna, L; GAMBACORTI PASSERINI, C
Targeted deletion of the muscular dystrophy gene myotilin does not perturb muscle structure or function in mice
2007 Moza, M; Mologni, L; Trokovic, R; Faulkner, G; Partanen, J; Carpen, O
Oncogenic fusion tyrosine kinases as molecular targets for anti-cancer therapy
2007 Gunby, R; Sala, E; Tartari, C; Puttini, M; GAMBACORTI PASSERINI, C; Mologni, L
Sorafenib functions to potently suppress RET tyrosine kinase activity by direct enzymatic inhibition and promoting RET lysosomal degradation independent of proteasomal targeting
2007 Plaza menacho, I; Mologni, L; Sala, E; GAMBACORTI PASSERINI, C; Magee, A; Links, T; Hofstra, R; Barford, D; Isacke, C
Inhibition of RET tyrosine kinase by SU5416
2006 Mologni, L; Sala, E; Cazzaniga, S; Rostagno, R; Kuoni, T; Puttini, M; Bain, J; Cleris, L; Redaelli, S; Riva, B; Formelli, F; Scapozza, L; GAMBACORTI PASSERINI, C
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