"Design and synthesis of relevant biomolecules for functionalization of biomaterial in tissue engineering"

Carbohydrates, glycoconjugates, and oligosaccharides are critical components of living systems and mediate a vast number of fundamental biological processes from complex cellular operations required to initiate and sustain life, to recognition events that are responsible for autoimmune diseases, organ rejection, and inflammation. This functional diversity is reflected in the diversity of carbohydrate structures. There is an increasing demand for efficient access to oligosaccharides and glycoconjugates to deepen our understanding of glycobiology and to expedite the development of therapeutic agents. Biomaterials science brings together researchers from diverse academic backgrounds. They must communicate clearly. Some disciplines that intersect in the development, study and application of biomaterials include: bioengineer, chemist, chemical engineer, electrical engineer, mechanical engineer, materials scientist, biologist, microbiologist, physician, veterinarian, ethicist, nurse, lawyer, regulatory specialist and venture capitalist. Bone tissue engineering has become a significant area of research, and as a result of emerging activity in this field, a new class of drugs has been introduced with excellent potential to stimulate bone formation and to induce new bone regeneration. Biodegradable scaffolds should ideally provide the initial strength required to resist blood flow, and then gradually degrade to leave a graft composed solely of host tissue.