First-episode psychosis is defined by the first treatment contact, with no previous antipsychotic medication use, due to the occurrence of psychotic symptoms or a psychotic episode. Psychosis involves any diagnosis included in the schizophrenia disorder cluster. Schizophrenia and other psychotic disorders are severe mental disorders characterized by delusions, hallucinations, disorganized speech and behaviour, and other symptoms that cause poor clinical outcomes and severe impairment in psychosocial functioning. Aetiology of schizophrenic disorders remain not entirely elucidated. Among possible causes, immunological factors have been increasingly involved in the pathogenesis and course of schizophrenia. The inflammatory system may trigger or modulate the course of schizophrenic disorders. Modifications in cytokine levels in schizophrenia and related psychotic disorders have been repeatedly described. However, the effect of antipsychotics on cytokine levels in drug naive patients remains, incompletely explored yet. The aim of this meta-analysis will be to estimate the effect of antipsychotic treatment on plasma levels of candidate, relevant peripheral cytokines in drug-naive patients with first-episode psychosis.

Capuzzi, E., Mazza, M., Bartoli, F., Crocamo, C., Clerici, M., Carra', G. (2016). Pre- and post-treatment levels of plasma cytokines in drug-naive patients with first-episode psychosis: a meta-analysis [Altro].

Pre- and post-treatment levels of plasma cytokines in drug-naive patients with first-episode psychosis: a meta-analysis

CAPUZZI, ENRICO
Primo
;
MAZZA, MARIO GENNARO;CROCAMO, CRISTINA;CLERICI, MASSIMO
Penultimo
;
CARRA', GIUSEPPE
Ultimo
;
2016

Abstract

First-episode psychosis is defined by the first treatment contact, with no previous antipsychotic medication use, due to the occurrence of psychotic symptoms or a psychotic episode. Psychosis involves any diagnosis included in the schizophrenia disorder cluster. Schizophrenia and other psychotic disorders are severe mental disorders characterized by delusions, hallucinations, disorganized speech and behaviour, and other symptoms that cause poor clinical outcomes and severe impairment in psychosocial functioning. Aetiology of schizophrenic disorders remain not entirely elucidated. Among possible causes, immunological factors have been increasingly involved in the pathogenesis and course of schizophrenia. The inflammatory system may trigger or modulate the course of schizophrenic disorders. Modifications in cytokine levels in schizophrenia and related psychotic disorders have been repeatedly described. However, the effect of antipsychotics on cytokine levels in drug naive patients remains, incompletely explored yet. The aim of this meta-analysis will be to estimate the effect of antipsychotic treatment on plasma levels of candidate, relevant peripheral cytokines in drug-naive patients with first-episode psychosis.
Altro
Scientifica
meta-analysis
First-episode Psychosis, Schizophrenia, cytokine, antipsychotic, immunological system
English
Capuzzi, E., Mazza, M., Bartoli, F., Crocamo, C., Clerici, M., Carra', G. (2016). Pre- and post-treatment levels of plasma cytokines in drug-naive patients with first-episode psychosis: a meta-analysis [Altro].
Capuzzi, E; Mazza, M; Bartoli, F; Crocamo, C; Clerici, M; Carra', G
File in questo prodotto:
File Dimensione Formato  
PROSPERO.pdf

accesso aperto

Dimensione 120.43 kB
Formato Adobe PDF
120.43 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/129432
Citazioni
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
Social impact