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Authors: Paulesu, E; Goldacre, B; Scifo, P; Cappa, SF; Gilardi, MC; Castiglioni, I; Perani,D; Fazio, F
Title: Functional heterogeneity of left inferior frontal cortex as revealed by fMRI
Abstract: Using functional magnetic resonance imaging (fMRI), we mapped brain activity in six normal volunteers during two silent verbal fluency tasks, one with a phonemic (letter) cue and one with a semantic (category) cue. In comparison with resting state, both tasks activated the anterior triangular portion of the left inferior frontal gyrus (IFG or F3, for third frontal gyrus) and the left thalamus. There were also areas activated in one task but not in the other: the posterior opercular portion of the left IFG for phonemic fluency, and the left retrosplenial region for semantic fluency. Our findings concur with normal psychophysical data and neuropsychological observations to suggest the recruitment of two overlapping but dissociable systems for the two tasks, and demonstrate functional heterogeneity within the left IFG (Broca's area), where the opercular portion is responsible for obtaining access to words through a phonemic/articulatory route.
Keywords: fMRI,
ISO Language : eng
Issue Date: 1997
Circulation: Rilevanza internazionale
Type: Articolo in rivista
Referee: Sì, ma tipo non specificato
Impact Factor: Con Impact Factor ISI
Publication Status: Pubblicato
DOI: 10.1006/brln.2000.2382
Citation: Paulesu, E., Goldacre, B., Scifo, P., Cappa, S.F., Gilardi, M.C., Castiglioni, I., et al. (1997). Functional heterogeneity of left inferior frontal cortex as revealed by fMRI. Neuroreport, 8(8), 2011-2016.
Appears in Collections:Pubblicazioni >01 - Articolo su rivista
Pubblicazioni precedenti al 1998 >01 - Articolo su rivista

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