A set of heterobifunctional oligo ethylene glycols have been synthesized in a straightforward and stepwise manner starting from inexpensive, commercially available, tetraethylene glycol. Introduction of terminal allyl moieties followed by reductive ozonolysis allowed controlled elongation. Mono-allyl derivatives were used for the elongation with a functionalized moiety and for successive introduction of different functional groups on the chain terminal

LA FERLA, B., Zona, C., D'Orazio, G. (2013). Controlled-length efficient synthesis of heterobifunctionalized oligo ethylene glycols. SYNLETT, 24(6), 709-712 [10.1055/s-0032-1318433].

Controlled-length efficient synthesis of heterobifunctionalized oligo ethylene glycols

LA FERLA, BARBARA;ZONA, CRISTIANO;D'ORAZIO, GIUSEPPE
2013

Abstract

A set of heterobifunctional oligo ethylene glycols have been synthesized in a straightforward and stepwise manner starting from inexpensive, commercially available, tetraethylene glycol. Introduction of terminal allyl moieties followed by reductive ozonolysis allowed controlled elongation. Mono-allyl derivatives were used for the elongation with a functionalized moiety and for successive introduction of different functional groups on the chain terminal
Articolo in rivista - Articolo scientifico
ethylene glycols, heterobifunctional, spacers, biomolecule grafting, elongation
English
2013
24
6
709
712
none
LA FERLA, B., Zona, C., D'Orazio, G. (2013). Controlled-length efficient synthesis of heterobifunctionalized oligo ethylene glycols. SYNLETT, 24(6), 709-712 [10.1055/s-0032-1318433].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/46366
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