We report two cases of severe refractory progressive chronic graft- versus-host disease (cGvHD) which improved dramatically after extracorporeal photochemotherapy. This procedure, based on functional changes of lymphocytes induced by 8-methoxypsoralen and UVA administered to leukapheresis collections, could be a useful treatment for cGvHD, even after many years of unsuccessful immunosuppressive approaches.

Biagi, E., Perseghin, P., Buscemi, F., Dassi, M., Rovelli, A., Balduzzi, A. (2000). Effectiveness of extracorporeal photochemotherapy in treating long-term refractory chronic graft-versus-host disease. HAEMATOLOGICA, 85(3), 329-330.

Effectiveness of extracorporeal photochemotherapy in treating long-term refractory chronic graft-versus-host disease

BIAGI, ETTORE;Balduzzi, A.
2000

Abstract

We report two cases of severe refractory progressive chronic graft- versus-host disease (cGvHD) which improved dramatically after extracorporeal photochemotherapy. This procedure, based on functional changes of lymphocytes induced by 8-methoxypsoralen and UVA administered to leukapheresis collections, could be a useful treatment for cGvHD, even after many years of unsuccessful immunosuppressive approaches.
Articolo in rivista - Articolo scientifico
Leukapheresis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Fanconi Anemia; Humans; Photochemotherapy; PUVA Therapy; Lymphocytes; Child, Preschool; Graft vs Host Disease; Chronic Disease; Adolescent; Female; Male
English
mar-2000
85
3
329
330
none
Biagi, E., Perseghin, P., Buscemi, F., Dassi, M., Rovelli, A., Balduzzi, A. (2000). Effectiveness of extracorporeal photochemotherapy in treating long-term refractory chronic graft-versus-host disease. HAEMATOLOGICA, 85(3), 329-330.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/46195
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