This article presents a process for surface coating and functionalization of luminescent silicon nanoparticles. The particles were coated with silica using a microemulsion process that was adapted to the fragile silicon nanoparticles. The as-produced core- shell particles have a mean diameter of 35 nm and exhibit the intrinsic photoluminescence of the silicon core. The silica layer protects the core from aqueous oxidation for several days, thus allowing the use of the nanoparticles for biological applications. The nanoparticles were further coated with amines and functionalized with polyethylene glycol chains and the toxicity of the particles has been evaluated at the different stages of the process. The core-shell nanoparticles exhibit no acute toxicity towards lung cells, which is promising for further development. © Springer Science+Business Media B.V. 2012.

Maurice, V., Rivolta, I., Vincent, J., Raccurt, O., Rouzaud, J., Miserocchi, G., et al. (2012). Silica encapsulation of luminescent silicon nanoparticles: Stable and biocompatible nanohybrids. JOURNAL OF NANOPARTICLE RESEARCH, 14(2), 697-705 [10.1007/s11051-011-0697-0].

Silica encapsulation of luminescent silicon nanoparticles: Stable and biocompatible nanohybrids

RIVOLTA, ILARIA;MISEROCCHI, GIUSEPPE ANDREA;
2012

Abstract

This article presents a process for surface coating and functionalization of luminescent silicon nanoparticles. The particles were coated with silica using a microemulsion process that was adapted to the fragile silicon nanoparticles. The as-produced core- shell particles have a mean diameter of 35 nm and exhibit the intrinsic photoluminescence of the silicon core. The silica layer protects the core from aqueous oxidation for several days, thus allowing the use of the nanoparticles for biological applications. The nanoparticles were further coated with amines and functionalized with polyethylene glycol chains and the toxicity of the particles has been evaluated at the different stages of the process. The core-shell nanoparticles exhibit no acute toxicity towards lung cells, which is promising for further development. © Springer Science+Business Media B.V. 2012.
Articolo in rivista - Articolo scientifico
nanoparticle, silicon, biocompatibility
English
2012
14
2
697
705
none
Maurice, V., Rivolta, I., Vincent, J., Raccurt, O., Rouzaud, J., Miserocchi, G., et al. (2012). Silica encapsulation of luminescent silicon nanoparticles: Stable and biocompatible nanohybrids. JOURNAL OF NANOPARTICLE RESEARCH, 14(2), 697-705 [10.1007/s11051-011-0697-0].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/45085
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