High-performance ion-exchange chromatography and immunoaffinity chromatography suggest that Par jI, the principal allergenic component of Parietaria judaica pollen, is a very unstable molecule, which tends to fragment in solution. Several fragments were obtained from Par jI and some of them show positivity toward the anti-Par jI monoclonal antibody, suggesting that they retain the entire structure of the allergenic determinant. These fragments could be the target for sequence and conformation studies.

Bolzacchini, E., DI GENNARO, P., Digregorio, G., Rindone, B., Falagiani, P., Mistrello, G., et al. (1991). Allergenic fragments in parietaria-judaica pollen extract. JOURNAL OF CHROMATOGRAPHY A, 542(2), 337-344 [10.1016/S0021-9673(01)88772-0].

Allergenic fragments in parietaria-judaica pollen extract

BOLZACCHINI, EZIO;DI GENNARO, PATRIZIA;RINDONE, BRUNO;
1991

Abstract

High-performance ion-exchange chromatography and immunoaffinity chromatography suggest that Par jI, the principal allergenic component of Parietaria judaica pollen, is a very unstable molecule, which tends to fragment in solution. Several fragments were obtained from Par jI and some of them show positivity toward the anti-Par jI monoclonal antibody, suggesting that they retain the entire structure of the allergenic determinant. These fragments could be the target for sequence and conformation studies.
Articolo in rivista - Articolo scientifico
Major Allergen; Identification; Purification; Officinalis; Antigens
English
1991
542
2
337
344
none
Bolzacchini, E., DI GENNARO, P., Digregorio, G., Rindone, B., Falagiani, P., Mistrello, G., et al. (1991). Allergenic fragments in parietaria-judaica pollen extract. JOURNAL OF CHROMATOGRAPHY A, 542(2), 337-344 [10.1016/S0021-9673(01)88772-0].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/33683
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