Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in children and adolescents. Survivors of severe TBI are more prone to functional deficits, resulting in poorer school performance, poor health-related quality of life (HRQoL), and increased risk of mental health problems. Critical gaps in knowledge of pathophysiological differences between children and adults concerning TBI outcomes, the paucity of pediatric trials and prognostic models and the uncertain extrapolation of adult data to pediatrics pose significant challenges and demand global efforts. Here, we explore the clinical and research unmet needs focusing on severe pediatric TBI to identify best practices in pathways of care and optimize both inpatient and outpatient management of children following TBI.

Nacoti, M., Fazzi, F., Biroli, F., Zangari, R., Barbui, T., Kochanek, P., et al. (2021). Addressing Key Clinical Care and Clinical Research Needs in Severe Pediatric Traumatic Brain Injury: Perspectives From a Focused International Conference. FRONTIERS IN PEDIATRICS, 8(18 January 2021) [10.3389/fped.2020.594425].

Addressing Key Clinical Care and Clinical Research Needs in Severe Pediatric Traumatic Brain Injury: Perspectives From a Focused International Conference

Citerio, Giuseppe;
2021

Abstract

Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in children and adolescents. Survivors of severe TBI are more prone to functional deficits, resulting in poorer school performance, poor health-related quality of life (HRQoL), and increased risk of mental health problems. Critical gaps in knowledge of pathophysiological differences between children and adults concerning TBI outcomes, the paucity of pediatric trials and prognostic models and the uncertain extrapolation of adult data to pediatrics pose significant challenges and demand global efforts. Here, we explore the clinical and research unmet needs focusing on severe pediatric TBI to identify best practices in pathways of care and optimize both inpatient and outpatient management of children following TBI.
Articolo in rivista - Review Essay
intracranial pressure; outcomes; pediatric; prognosis; traumatic brain injury;
English
18-gen-2021
2021
8
18 January 2021
594425
open
Nacoti, M., Fazzi, F., Biroli, F., Zangari, R., Barbui, T., Kochanek, P., et al. (2021). Addressing Key Clinical Care and Clinical Research Needs in Severe Pediatric Traumatic Brain Injury: Perspectives From a Focused International Conference. FRONTIERS IN PEDIATRICS, 8(18 January 2021) [10.3389/fped.2020.594425].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/301638
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