Temperature dependence data for physical-chemical properties is increasingly required for modelling the fate of chemicals in the environment. Solubility and octanol-water partition coefficient (K-ow) are among the most important parameters. A simple and fast method is presented to determine solubility and K., of organic chemicals at different temperatures (5 degreesC, 15 degreesC 25 degreesC, 35 degreesC) utilising a variable temperature RP-HPLC column. Correlations between capacity factors (k(i)) and solubility and K-ow were determined for some halogenated and methylated benzenes and showed that this approach could be used to predict acceptable results. New values for solubility and K-ow as function of temperature for several compounds are presented. (C) 2001 Elsevier Science Ltd. All rights reserved

Finizio, A., Di Guardo, A. (2001). Estimating temperature dependence of solubility and octanol-water partition coefficient for organic compounds using RP-HPLC. CHEMOSPHERE, 45(6), 1063-1070 [10.1016/S0045-6535(01)00105-9].

Estimating temperature dependence of solubility and octanol-water partition coefficient for organic compounds using RP-HPLC

Finizio, A;
2001

Abstract

Temperature dependence data for physical-chemical properties is increasingly required for modelling the fate of chemicals in the environment. Solubility and octanol-water partition coefficient (K-ow) are among the most important parameters. A simple and fast method is presented to determine solubility and K., of organic chemicals at different temperatures (5 degreesC, 15 degreesC 25 degreesC, 35 degreesC) utilising a variable temperature RP-HPLC column. Correlations between capacity factors (k(i)) and solubility and K-ow were determined for some halogenated and methylated benzenes and showed that this approach could be used to predict acceptable results. New values for solubility and K-ow as function of temperature for several compounds are presented. (C) 2001 Elsevier Science Ltd. All rights reserved
Articolo in rivista - Articolo scientifico
K-ow; solubility estimation method; chlorobenzenes; methylbenzenes
English
2001
45
6
1063
1070
none
Finizio, A., Di Guardo, A. (2001). Estimating temperature dependence of solubility and octanol-water partition coefficient for organic compounds using RP-HPLC. CHEMOSPHERE, 45(6), 1063-1070 [10.1016/S0045-6535(01)00105-9].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/28648
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