Cerebral amyloid angiopathy-related inflammation (CAA-ri) is a rare and treatable variant of CAA likely due to an autoimmune response directed toward beta-amyloid deposits. Cognitive and behavioral manifestations are the most common symptoms, followed by focal neurological signs, headache and seizures, associated with characteristics neuroradiological features on brain magnetic resonance imaging (MRI). We describe the clinical course, radiological features and therapeutic approach of two patients with probable CAA-ri with the aim of emphasizing the importance of an early diagnosis of this potentially reversible disease in different neurological settings, such as memory clinics and stroke units.

Poli, L., De Giuli, V., Piazza, F., Volonghi, I., Bigliardi, G., Vallone, S., et al. (2020). A challenging diagnosis of reversible “vascular” dementia: Cerebral amyloid angiopathy-related inflammation. JOURNAL OF NEUROIMMUNOLOGY, 338(15 January 2020) [10.1016/j.jneuroim.2019.577109].

A challenging diagnosis of reversible “vascular” dementia: Cerebral amyloid angiopathy-related inflammation

Piazza F.;
2020

Abstract

Cerebral amyloid angiopathy-related inflammation (CAA-ri) is a rare and treatable variant of CAA likely due to an autoimmune response directed toward beta-amyloid deposits. Cognitive and behavioral manifestations are the most common symptoms, followed by focal neurological signs, headache and seizures, associated with characteristics neuroradiological features on brain magnetic resonance imaging (MRI). We describe the clinical course, radiological features and therapeutic approach of two patients with probable CAA-ri with the aim of emphasizing the importance of an early diagnosis of this potentially reversible disease in different neurological settings, such as memory clinics and stroke units.
Articolo in rivista - Articolo scientifico
Cerebral Amyloid Angiopathy; Cerebral Hemorrhage; Angiopathy CAA; Cerebral amyloid angiopathy related inflammation; CAA-ri; ARIA; iCAB International Network;
English
6-nov-2019
2020
338
15 January 2020
577109
open
Poli, L., De Giuli, V., Piazza, F., Volonghi, I., Bigliardi, G., Vallone, S., et al. (2020). A challenging diagnosis of reversible “vascular” dementia: Cerebral amyloid angiopathy-related inflammation. JOURNAL OF NEUROIMMUNOLOGY, 338(15 January 2020) [10.1016/j.jneuroim.2019.577109].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/251409
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