The simplified synthesis of a portion of Globo-H hexasaccharide, a saccharide antigen overexpressed by breast cancer cells, and its conjugation to two different immunogenic proteins are described. The conjugated vaccines, evaluated in a preclinical model, showed good immunogenic potential

Panza, L., Poletti, L., Prosperi, D., Canevari, S., Perico, M. (2001). Improvement of the synthesis of immunologic carbohydrate vaccines containing the tumor associated antigen CaMBr1. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY(22), 4331-4336 [10.1002/1099-0690(200111)2001:22<4331::AID-EJOC4331>3.0.CO;2-R].

Improvement of the synthesis of immunologic carbohydrate vaccines containing the tumor associated antigen CaMBr1

PROSPERI, DAVIDE;
2001

Abstract

The simplified synthesis of a portion of Globo-H hexasaccharide, a saccharide antigen overexpressed by breast cancer cells, and its conjugation to two different immunogenic proteins are described. The conjugated vaccines, evaluated in a preclinical model, showed good immunogenic potential
Articolo in rivista - Articolo scientifico
sintesi organica; antitumorali; immunologia
English
2001
22
4331
4336
none
Panza, L., Poletti, L., Prosperi, D., Canevari, S., Perico, M. (2001). Improvement of the synthesis of immunologic carbohydrate vaccines containing the tumor associated antigen CaMBr1. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY(22), 4331-4336 [10.1002/1099-0690(200111)2001:22<4331::AID-EJOC4331>3.0.CO;2-R].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/24694
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