Purpose: To assess the risk of illnesses and accidents in patients with epilepsy and to evaluate the proportion of those risks attributable to epilepsy. Methods: Nine hundred fifty-one referral patients with idiopathic, cryptogenic, or remote symptomatic epilepsy and 909 matched controls (relatives or friends) were followed up prospectively for 1-2 years in eight European countries (Italy, Germany, Holland, England, Portugal, Russia, Estonia, and Slovenia). Each patient and control received a diary to keep notes regarding any illness or accident. Patients with epilepsy specifically recorded relations with seizures. Results: Six hundred forty-four patients recorded 2,491 illnesses compared with 1,665 illnesses in 508 controls. The cumulative probability of illness in patients was 49% by 12 months and 86% by 24 months (controls, 39 and 75%; p < 0.0001). One hundred ninety-nine patients and 124 controls had 270 and 140 accidents, respectively. The Cumulative probability of accident in the cases was 17 and 27% by 12 and 24 months (controls. 12 and 17%; p < 0.0001). The chance of two or more illnesses or accidents was modestly but significantly greater in the patients. Illnesses and accidents were mostly trivial. Thirty percent of illnesses and 24% of accidents were seizure related. When illnesses and accidents related to seizures were excluded, the chance of illnesses and accidents was fairly similar in the two groups, Conclusions: Patients with idiopathic. cryptogenic, or remote symptomatic epilepsy have a moderately higher risk of illnesses and accidents than do the general Population. With few exceptions, the events are trivial. When seizure-related events are excluded. patients with epilepsy are not at any significantly higher risk of illnesses and accidents

Beghi, E., Cornaggia, C. (2002). Morbidity and accidents in patients with epilepsy: Results of a European cohort study. EPILEPSIA, 43(9), 1076-1083 [10.1046/j.1528-1157.2002.18701.x].

Morbidity and accidents in patients with epilepsy: Results of a European cohort study

Cornaggia, CM
2002

Abstract

Purpose: To assess the risk of illnesses and accidents in patients with epilepsy and to evaluate the proportion of those risks attributable to epilepsy. Methods: Nine hundred fifty-one referral patients with idiopathic, cryptogenic, or remote symptomatic epilepsy and 909 matched controls (relatives or friends) were followed up prospectively for 1-2 years in eight European countries (Italy, Germany, Holland, England, Portugal, Russia, Estonia, and Slovenia). Each patient and control received a diary to keep notes regarding any illness or accident. Patients with epilepsy specifically recorded relations with seizures. Results: Six hundred forty-four patients recorded 2,491 illnesses compared with 1,665 illnesses in 508 controls. The cumulative probability of illness in patients was 49% by 12 months and 86% by 24 months (controls, 39 and 75%; p < 0.0001). One hundred ninety-nine patients and 124 controls had 270 and 140 accidents, respectively. The Cumulative probability of accident in the cases was 17 and 27% by 12 and 24 months (controls. 12 and 17%; p < 0.0001). The chance of two or more illnesses or accidents was modestly but significantly greater in the patients. Illnesses and accidents were mostly trivial. Thirty percent of illnesses and 24% of accidents were seizure related. When illnesses and accidents related to seizures were excluded, the chance of illnesses and accidents was fairly similar in the two groups, Conclusions: Patients with idiopathic. cryptogenic, or remote symptomatic epilepsy have a moderately higher risk of illnesses and accidents than do the general Population. With few exceptions, the events are trivial. When seizure-related events are excluded. patients with epilepsy are not at any significantly higher risk of illnesses and accidents
Articolo in rivista - Articolo scientifico
epilepsy; morbidity; accidents; injuries; illnesses
English
2002
43
9
1076
1083
none
Beghi, E., Cornaggia, C. (2002). Morbidity and accidents in patients with epilepsy: Results of a European cohort study. EPILEPSIA, 43(9), 1076-1083 [10.1046/j.1528-1157.2002.18701.x].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/22876
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