Silica-encapsulated iron oxide composite nanoparticles were synthesized and characterized in terms of morphological and physico-chemical properties. These nanoparticles exhibited both fluorescent and magnetic properties useful for labeling of breast cancer cells. The mechanism of uptake by tumor cells, the pathway of degradation and the potential toxicity of these magnetofluorescent nanoparticles were investigated, suggesting that they could be developed as an efficient and safe bimodal contrast agent for detection of breast cancer cells. © 2010 American Institute of Physics.
Ronchi, S., Colombo, M., Verderio, P., Mazzucchelli, S., Corsi, F., De Palma, C., et al. (2010). Magnetofluorescent nanoparticles for bimodal detection of breast cancer cells. In Bonsai project symposium: breakthroughs in nanoparticles for bio-imaging (pp.102-105). American Institute of Physics [10.1063/1.3505055].
Magnetofluorescent nanoparticles for bimodal detection of breast cancer cells
COLOMBO, MIRIAM;PROSPERI, DAVIDE
2010
Abstract
Silica-encapsulated iron oxide composite nanoparticles were synthesized and characterized in terms of morphological and physico-chemical properties. These nanoparticles exhibited both fluorescent and magnetic properties useful for labeling of breast cancer cells. The mechanism of uptake by tumor cells, the pathway of degradation and the potential toxicity of these magnetofluorescent nanoparticles were investigated, suggesting that they could be developed as an efficient and safe bimodal contrast agent for detection of breast cancer cells. © 2010 American Institute of Physics.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
