We present the synthesis of trastuzumab-functionalized pegylated iron oxide nanoparticles and provide an FTIR-based approach to gain a direct evidence of the actual conservation of the native structure of conjugated antibody. Their target-selectivity to specific cancer cell receptors has been also assessed

Occhipinti, E., Verderio, P., Natalello, A., Galbiati, E., Colombo, M., Mazzucchelli, S., et al. (2011). Investigating the structural biofunctionality of antibodies conjugated to magnetic nanoparticles. NANOSCALE, 3(2), 387-390 [10.1039/C0NR00436G].

Investigating the structural biofunctionality of antibodies conjugated to magnetic nanoparticles

NATALELLO, ANTONINO;COLOMBO, MIRIAM;TORTORA, PAOLO;DOGLIA, SILVIA MARIA;PROSPERI, DAVIDE
2011

Abstract

We present the synthesis of trastuzumab-functionalized pegylated iron oxide nanoparticles and provide an FTIR-based approach to gain a direct evidence of the actual conservation of the native structure of conjugated antibody. Their target-selectivity to specific cancer cell receptors has been also assessed
Articolo in rivista - Articolo scientifico
anticorpi; Nanobiotecnologie; nanoparticelle; bioconiugazione; biofisica; FTIR
English
2011
3
2
387
390
none
Occhipinti, E., Verderio, P., Natalello, A., Galbiati, E., Colombo, M., Mazzucchelli, S., et al. (2011). Investigating the structural biofunctionality of antibodies conjugated to magnetic nanoparticles. NANOSCALE, 3(2), 387-390 [10.1039/C0NR00436G].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/20668
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