This preliminary study aims to establish the Virtual Chromoendoscopic Magnification (VCM) feasibility to visualize and distinguish the Intraepithelial Papillary Capillary Loops (IPCL) patterns of benign oral pathologies from malignant ones. Thirty-one consecutive subjects affected by oral lesions/pathologies underwent white light examination and VCM imaging by the Narrow Band Imaging System (Olympus Medical Systems Corp., Tokyo, Japan). A class system of four IPCL types corresponding to progressive vessel disarray was adopted. IPCL type IV were considered criterion of "malignancy". A histopathological exam completed the diagnosis: sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were calculated. IPCL patterns of benign oral entities ranged from types I to III. IPCL type IV was associated with malignancy in 4 out of 6 cases. Sensitivity, specificity, PPV, and NPV were 100%, 93%, 67% and 100%, respectively. This study preliminarily describes IPCL patterns of different oral mucosal diseases and confirms the association between IPCL IV and oral cancer.

Contaldo, M., Lucchese, A., Gentile, E., Zulli, C., Petruzzi, M., Lauritano, D., et al. (2017). Evaluation of the intraepithelial papillary capillary loops in benign & malignant oral lesions by in vivo virtual chromoendoscopic magnification: A preliminary study. JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS, 31(2), 11-22.

Evaluation of the intraepithelial papillary capillary loops in benign & malignant oral lesions by in vivo virtual chromoendoscopic magnification: A preliminary study

Lauritano, D;
2017

Abstract

This preliminary study aims to establish the Virtual Chromoendoscopic Magnification (VCM) feasibility to visualize and distinguish the Intraepithelial Papillary Capillary Loops (IPCL) patterns of benign oral pathologies from malignant ones. Thirty-one consecutive subjects affected by oral lesions/pathologies underwent white light examination and VCM imaging by the Narrow Band Imaging System (Olympus Medical Systems Corp., Tokyo, Japan). A class system of four IPCL types corresponding to progressive vessel disarray was adopted. IPCL type IV were considered criterion of "malignancy". A histopathological exam completed the diagnosis: sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were calculated. IPCL patterns of benign oral entities ranged from types I to III. IPCL type IV was associated with malignancy in 4 out of 6 cases. Sensitivity, specificity, PPV, and NPV were 100%, 93%, 67% and 100%, respectively. This study preliminarily describes IPCL patterns of different oral mucosal diseases and confirms the association between IPCL IV and oral cancer.
Articolo in rivista - Articolo scientifico
virtual chromoendoscopic magnification; narrow band imaging; oral cancer; oral pathology; non-invasive imaging
English
2017
31
2
11
22
reserved
Contaldo, M., Lucchese, A., Gentile, E., Zulli, C., Petruzzi, M., Lauritano, D., et al. (2017). Evaluation of the intraepithelial papillary capillary loops in benign & malignant oral lesions by in vivo virtual chromoendoscopic magnification: A preliminary study. JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS, 31(2), 11-22.
File in questo prodotto:
File Dimensione Formato  
310 EVALUATION OF THE INTRAEPITHELIAL PAPILLARY CAPILLARY LOOPS IN BENIGN AND MALIGNANT ORAL LESIONS BY IN VIVO VIRTUAL CHROMOENDOSCOPIC MAGNIFICATION.pdf

Solo gestori archivio

Descrizione: Articolo principale
Dimensione 684.3 kB
Formato Adobe PDF
684.3 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/172698
Citazioni
  • Scopus 31
  • ???jsp.display-item.citation.isi??? 23
Social impact