Previous studies indicate that arterial baroreceptor modulation of heart rate is drastically reduced during static or dynamic exercise. We have investigated whether this reduction also occurs with regard to blood pressure modulation by the baroreflex. The study was performed in 19 subjects with uncomplicated untreated essential hypertension in whom blood pressure was measured intraarterially, and R-R interval was obtained by an electrocardiogram. The carotid baroreceptors were stimulated by neck suction of 30 seconds' duration, and equal stimuli were applied at rest and during hand-grip exercise performed at 40% of the subjects' maximal strength. Baroreceptor stimulation at rest increased R-R interval and reduced blood pressure. During hand-grip, the R-R interval responses to the baroreceptor stimulus were diminished by 61%. In contrast, the blood pressure responses were not significantly altered. Similar results were obtained when two subgroups of subjects with a lesser or greater degree of hypertension were separately considered. Thus, the carotid baroreceptor influence on blood pressure is largely preserved during exercise in contrast to the carotid baroreceptor influence on the sinus node, which is markedly impaired

Mancia, G., Ferrari, A., Gregorini, L., Parati, G., Pomidossi, G. (1982). Effects of isometric exercise on the carotid baroreflex in hypertensive subjects. HYPERTENSION, 4(2), 245-250 [10.1161/01.HYP.4.2.245].

Effects of isometric exercise on the carotid baroreflex in hypertensive subjects

MANCIA, GIUSEPPE
Primo
;
FERRARI, ALBERTO
Secondo
;
PARATI, GIANFRANCO
Penultimo
;
1982

Abstract

Previous studies indicate that arterial baroreceptor modulation of heart rate is drastically reduced during static or dynamic exercise. We have investigated whether this reduction also occurs with regard to blood pressure modulation by the baroreflex. The study was performed in 19 subjects with uncomplicated untreated essential hypertension in whom blood pressure was measured intraarterially, and R-R interval was obtained by an electrocardiogram. The carotid baroreceptors were stimulated by neck suction of 30 seconds' duration, and equal stimuli were applied at rest and during hand-grip exercise performed at 40% of the subjects' maximal strength. Baroreceptor stimulation at rest increased R-R interval and reduced blood pressure. During hand-grip, the R-R interval responses to the baroreceptor stimulus were diminished by 61%. In contrast, the blood pressure responses were not significantly altered. Similar results were obtained when two subgroups of subjects with a lesser or greater degree of hypertension were separately considered. Thus, the carotid baroreceptor influence on blood pressure is largely preserved during exercise in contrast to the carotid baroreceptor influence on the sinus node, which is markedly impaired
Articolo in rivista - Articolo scientifico
Adult; Aged; Blood Pressure; Carotid Sinus; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Pressoreceptors; Reflex; Isometric Contraction; Physical Exertion
English
1982
4
2
245
250
none
Mancia, G., Ferrari, A., Gregorini, L., Parati, G., Pomidossi, G. (1982). Effects of isometric exercise on the carotid baroreflex in hypertensive subjects. HYPERTENSION, 4(2), 245-250 [10.1161/01.HYP.4.2.245].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/170920
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