Microbeam irradiation is spatially fractionated radiation on a micrometer scale. Microbeam irradiation with therapeutic intent has become known as microbeam radiation therapy (MRT). The basic concept of MRT was developed in the 1980s, but it has not yet been tested in any human clinical trial, even though there is now a large number of animal studies demonstrating its marked therapeutic potential with an exceptional normal tissue sparing effect. Furthermore, MRT is conceptually similar to macroscopic grid based radiation therapy which has been used in clinical practice for decades. In this review, the potential clinical applications of MRT are analysed for both malignant and non-malignant diseases.

Schültke, E., Balosso, J., Breslin, T., Cavaletti, G., Djonov, V., Esteve, F., et al. (2017). Microbeam radiation therapy - Grid therapy and beyond: A clinical perspective. BRITISH JOURNAL OF RADIOLOGY, 90(1078) [10.1259/bjr.20170073].

Microbeam radiation therapy - Grid therapy and beyond: A clinical perspective

Cavaletti, G;
2017

Abstract

Microbeam irradiation is spatially fractionated radiation on a micrometer scale. Microbeam irradiation with therapeutic intent has become known as microbeam radiation therapy (MRT). The basic concept of MRT was developed in the 1980s, but it has not yet been tested in any human clinical trial, even though there is now a large number of animal studies demonstrating its marked therapeutic potential with an exceptional normal tissue sparing effect. Furthermore, MRT is conceptually similar to macroscopic grid based radiation therapy which has been used in clinical practice for decades. In this review, the potential clinical applications of MRT are analysed for both malignant and non-malignant diseases.
Articolo in rivista - Articolo scientifico
microbeam radiation therapy;
English
2017
90
1078
20170073
open
Schültke, E., Balosso, J., Breslin, T., Cavaletti, G., Djonov, V., Esteve, F., et al. (2017). Microbeam radiation therapy - Grid therapy and beyond: A clinical perspective. BRITISH JOURNAL OF RADIOLOGY, 90(1078) [10.1259/bjr.20170073].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/164969
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