Objectives The World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have proposed eight recommendations for cancer prevention, related to body fatness, diet, and physical activity. Our aim is to evaluate the role of adherence to these recommendations on head and neck cancers risk. Materials and methods We obtained an overall score including seven of the WCRF/AICR recommendations, and examined its relationship with head and neck cancers risk in two Italian case-control studies including 946 patients with oral cavity and pharyngeal (OCP) cancer and 2492 controls, and 689 patients with laryngeal cancer and 1605 controls. Results Higher adherence to WCRF/AICR recommendations was associated to a reduced risk of OCP cancer (odds ratio, OR = 0.45, 95% confidence interval, CI: 0.33–0.62 for a score of 4–<5, and OR = 0.32, 95% CI: 0.22–0.49 for a score of ⩾5 as compared to <3). The ORs for laryngeal cancer were 0.68 (95% CI: 0.50–0.92) for a score of 3–<4, 0.39 (95% CI: 0.28–0.55) for a score of 4–<5, and 0.24 (95% CI: 0.15–0.38) for a score of ⩾5. Conclusion Our study indicates that high adherence to the WCRF/AICR recommendations for cancer prevention is associated with a substantially decreased risk of head and neck cancers.

Bravi, F., Polesel, J., Garavello, W., Serraino, D., Negri, E., Franchin, G., et al. (2017). Adherence to the World Cancer Research Fund/American Institute for Cancer Research recommendations and head and neck cancers risk. ORAL ONCOLOGY, 64, 59-64 [10.1016/j.oraloncology.2016.11.012].

Adherence to the World Cancer Research Fund/American Institute for Cancer Research recommendations and head and neck cancers risk

GARAVELLO, WERNER;
2017

Abstract

Objectives The World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) have proposed eight recommendations for cancer prevention, related to body fatness, diet, and physical activity. Our aim is to evaluate the role of adherence to these recommendations on head and neck cancers risk. Materials and methods We obtained an overall score including seven of the WCRF/AICR recommendations, and examined its relationship with head and neck cancers risk in two Italian case-control studies including 946 patients with oral cavity and pharyngeal (OCP) cancer and 2492 controls, and 689 patients with laryngeal cancer and 1605 controls. Results Higher adherence to WCRF/AICR recommendations was associated to a reduced risk of OCP cancer (odds ratio, OR = 0.45, 95% confidence interval, CI: 0.33–0.62 for a score of 4–<5, and OR = 0.32, 95% CI: 0.22–0.49 for a score of ⩾5 as compared to <3). The ORs for laryngeal cancer were 0.68 (95% CI: 0.50–0.92) for a score of 3–<4, 0.39 (95% CI: 0.28–0.55) for a score of 4–<5, and 0.24 (95% CI: 0.15–0.38) for a score of ⩾5. Conclusion Our study indicates that high adherence to the WCRF/AICR recommendations for cancer prevention is associated with a substantially decreased risk of head and neck cancers.
Articolo in rivista - Articolo scientifico
American Institute for Cancer Research; Case control study; Diet; Head and neck cancer; Risk factors; World Cancer Research Fund;
American Institute for Cancer Research; Case control study; Diet; Head and neck cancer; Risk factors; World Cancer Research Fund; Oral Surgery; Oncology; Cancer Research
English
2017
64
59
64
none
Bravi, F., Polesel, J., Garavello, W., Serraino, D., Negri, E., Franchin, G., et al. (2017). Adherence to the World Cancer Research Fund/American Institute for Cancer Research recommendations and head and neck cancers risk. ORAL ONCOLOGY, 64, 59-64 [10.1016/j.oraloncology.2016.11.012].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/140922
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