Blood pressure control is the cornerstone of therapeutic interventions aimed at preventing first strokes and recurrent strokes. All antihypertensive drug classes may be useful in preventing cerebrovascular events, depending on their efficacy in lowering elevated blood pressure values and achieving blood pressure control. However, recent findings indicate that drugs acting on the renin-angiotensin system (-angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers) may exert cerebrovascular protective effects in addition to blood pressure reduction. This article examines the cerebrovascular protection provided by antihypertensive drug treatment in the light of the results of recent meta-analyses and of the findings of the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial.

Grassi, G., QUARTI TREVANO, F., Dell'Oro, R., Mancia, G. (2009). Antihypertensive treatment and stroke prevention: From recent meta-analyses to the PRoFESS trial. CURRENT HYPERTENSION REPORTS, 11(4), 265-270.

Antihypertensive treatment and stroke prevention: From recent meta-analyses to the PRoFESS trial

GRASSI, GUIDO;QUARTI TREVANO, FOSCA ANNA LUISA;DELL'ORO, RAFFAELLA;MANCIA, GIUSEPPE
2009

Abstract

Blood pressure control is the cornerstone of therapeutic interventions aimed at preventing first strokes and recurrent strokes. All antihypertensive drug classes may be useful in preventing cerebrovascular events, depending on their efficacy in lowering elevated blood pressure values and achieving blood pressure control. However, recent findings indicate that drugs acting on the renin-angiotensin system (-angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers) may exert cerebrovascular protective effects in addition to blood pressure reduction. This article examines the cerebrovascular protection provided by antihypertensive drug treatment in the light of the results of recent meta-analyses and of the findings of the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial.
Articolo in rivista - Articolo scientifico
Meta-Analysis as Topic; Blood Pressure; Antihypertensive Agents; Hypertension; Stroke; Humans
English
2009
11
4
265
270
none
Grassi, G., QUARTI TREVANO, F., Dell'Oro, R., Mancia, G. (2009). Antihypertensive treatment and stroke prevention: From recent meta-analyses to the PRoFESS trial. CURRENT HYPERTENSION REPORTS, 11(4), 265-270.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/10107
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