Sfoglia per Autore
Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding
2024 Pizzul, P; Casari, E; Rinaldi, C; Gnugnoli, M; Mangiagalli, M; Tisi, R; Longhese, M
The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase
2023 Rinaldi, C; Pizzul, P; Casari, E; Mangiagalli, M; Tisi, R; Longhese, M
The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation
2023 Casari, E; Pizzul, P; Rinaldi, C; Gnugnoli, M; Clerici, M; Longhese, M
To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks
2022 Casari, E; Gnugnoli, M; Rinaldi, C; Pizzul, P; Colombo, C; Bonetti, D; Longhese, M
The DNA damage checkpoint: A tale from budding yeast
2022 Pizzul, P; Casari, E; Gnugnoli, M; Rinaldi, C; Corallo, F; Longhese, M
Sensing R-Loop-Associated DNA Damage to Safeguard Genome Stability
2021 Rinaldi, C; Pizzul, P; Longhese, M; Bonetti, D
Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes
2021 Casari, E; Gobbini, E; Gnugnoli, M; Mangiagalli, M; Clerici, M; Longhese, M
Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends
2021 Bonetti, D; Clerici, M; Longhese, M
The regulation of the DNA damage response at telomeres: Focus on kinases
2021 Galli, M; Frigerio, C; Longhese, M; Clerici, M
Resection of a DNA Double-Strand Break by Alkaline Gel Electrophoresis and Southern Blotting
2021 Casari, E; Gobbini, E; Clerici, M; Longhese, M
Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners
2021 Marsella, A; Gobbini, E; Cassani, C; Tisi, R; Cannavo, E; Reginato, G; Cejka, P; Longhese, M
The chromatin remodeler Chd1 supports MRX and Exo1 functions in resection of DNA double-strand breaks
2021 Gnugnoli, M; Casari, E; Longhese, M
DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends
2020 Bonetti, D; Rinaldi, C; Vertemara, J; Notaro, M; Pizzul, P; Tisi, R; Zampella, G; Longhese, M
Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks
2020 Tisi, R; Vertemara, J; Zampella, G; Longhese, M
How do cells sense DNA lesions?
2020 Colombo, C; Gnugnoli, M; Gobbini, E; Longhese, M
The 9-1-1 Complex Controls Mre11 Nuclease and Checkpoint Activation during Short-Range Resection of DNA Double-Strand Breaks
2020 Gobbini, E; Casari, E; Colombo, C; Bonetti, D; Longhese, M
The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing
2020 Bruhn, C; Ajazi, A; Ferrari, E; Lanz, M; Batrin, R; Choudhary, R; Walvekar, A; Laxman, S; Longhese, M; Fabre, E; Smolka, M; Foiani, M
Processing of DNA double-strand breaks by the MRX complex in a chromatin context
2019 Casari, E; Rinaldi, C; Marsella, A; Gnugnoli, M; Colombo, C; Bonetti, D; Longhese, M
The ATP-bound conformation of the Mre11-Rad50 complex is essential for Tel1/ATM activation
2019 Cassani, C; Vertemara, J; Bassani, M; Marsella, A; Tisi, R; Zampella, G; Longhese, M
Structure–function relationships of the Mre11 protein in the control of DNA end bridging and processing
2019 Marsella, A; Cassani, C; Casari, E; Tisi, R; Longhese, M
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