Sfoglia per Autore
High-throughput screening as a drug repurposing strategy for poor outcome subgroups of pediatric B-cell precursor Acute Lymphoblastic Leukemia
2023 Oikonomou, A; Valsecchi, L; Quadri, M; Watrin, T; Scharov, K; Procopio, S; Tu, J; Vogt, M; Savino, A; Silvestri, D; Valsecchi, M; Biondi, A; Borkhardt, A; Bhatia, S; Cazzaniga, G; Fazio, G; Bardini, M; Palmi, C
PAX5 fusion genes are frequent in poor risk childhood acute lymphoblastic leukaemia and can be targeted with BIBF1120
2022 Fazio, G; Bresolin, S; Silvestri, D; Quadri, M; Saitta, C; Vendramini, E; Buldini, B; Palmi, C; Bardini, M; Grioni, A; Rigamonti, S; Galbiati, M; Mecca, S; Savino, A; Peloso, A; Tu, J; Bhatia, S; Borkhardt, A; Micalizzi, C; Lo Nigro, L; Locatelli, F; Conter, V; Rizzari, C; Valsecchi, M; Te Kronnie, G; Biondi, A; Cazzaniga, G
The bone marrow niche in b-cell acute lymphoblastic leukemia: The role of microenvironment from pre-leukemia to overt leukemia
2021 Dander, E; Palmi, C; D'Amico, G; Cazzaniga, G
Recurrent genetic fusions redefine MLL germ line acute lymphoblastic leukemia in infants
2021 Fazio, G; Bardini, M; De Lorenzo, P; Grioni, A; Quadri, M; Pedace, L; Corral Abascal, L; Palamini, S; Palmi, C; Buldini, B; Vinti, L; Parasole, R; Barisone, E; Zecca, M; Favre, C; Locatelli, F; Conter, V; Rizzari, C; Valsecchi, M; Biondi, A; Cazzaniga, G
Inhibition of inflammatory signaling in Pax5 mutant cells mitigates B-cell leukemogenesis
2020 Isidro-Hernandez, M; Mayado, A; Casado-Garcia, A; Martinez-Cano, J; Palmi, C; Fazio, G; Orfao, A; Ribera, J; Ribera, J; Zamora, L; Raboso-Gallego, J; Blanco, O; Alonso-Lopez, D; De Las Rivas, J; Jimenez, R; Garcia Criado, F; Garcia Cenador, M; Ramirez-Orellana, M; Cazzaniga, G; Cobaleda, C; Vicente-Duenas, C; Sanchez-Garcia, I
Pro-inflammatory cytokines favor the emergence of ETV6-RUNX1-positive pre-leukemic cells in a model of mesenchymal niche
2020 Beneforti, L; Dander, E; Bresolin, S; Bueno, C; Acunzo, D; Bertagna, M; Ford, A; Gentner, B; Kronnie, G; Vergani, P; Menendez, P; Biondi, A; D'Amico, G; Palmi, C; Cazzaniga, G
Activin A contributes to the definition of a pro-oncogenic bone marrow microenvironment in t(12;21) preleukemia
2019 Portale, F; Beneforti, L; Fallati, A; Biondi, A; Palmi, C; Cazzaniga, G; Dander, E; D'Amico, G
IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia
2019 Lopes, B; Meyer, C; Barbosa, T; Poubel, C; Mansur, M; Duployez, N; Bashton, M; Harrison, C; zur Stadt, U; Horstmann, M; Pombo-de-Oliveira, M; Palmi, C; Cazzaniga, G; Venn, N; Sutton, R; Alonso, C; Tsaur, G; Gupta, S; Bakhshi, S; Marschalek, R; Emerenciano, M
IKZF1 plus defines a new minimal residual disease-dependent very-poor prognostic profile in pediatric b-cell precursor acute lymphoblastic leukemia
2018 Stanulla, M; Dagdan, E; Zaliova, M; Möricke, A; Palmi, C; Cazzaniga, G; Eckert, C; Te Kronnie, G; Bourquin, J; Bornhauser, B; Koehler, R; Bartram, C; Ludwig, W; Bleckmann, K; Groeneveld-Krentz, S; Schewe, D; Junk, S; Hinze, L; Klein, N; Kratz, C; Biondi, A; Borkhardt, A; Kulozik, A; Muckenthaler, M; Basso, G; Valsecchi, M; Izraeli, S; Petersen, B; Franke, A; Dörge, P; Steinemann, D; Haas, O; Panzer-Grümayer, R; Cavé, H; Houlston, R; Cario, G; Schrappe, M; Zimmermann, M
SRC/ABL inhibition disrupts CRLF2-driven signaling to induce cell death in B-cell acute lymphoblastic leukemia
2018 Sarno, J; Savino, A; Buracchi, C; Palmi, C; Pinto, S; Bugarin, C; Jager, A; Bresolin, S; Barber, R; Silvestri, D; Israeli, S; Dyer, M; Cazzaniga, G; Nolan, G; Biondi, A; Davis, K; Gaipa, G
Phosphoproteomic analysis reveals hyperactivation of mTOR/STAT3 and LCK/Calcineurin axes in pediatric early T-cell precursor ALL
2017 Serafin, V; Lissandron, V; Buldini, B; Bresolin, S; Paganin, M; Grillo, F; Andriano, N; Palmi, C; Cazzaniga, G; Marmiroli, S; Conter, V; Basso, G; Accordi, B
Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome
2017 Schwartzman, O; Savino, A; Gombert, M; Palmi, C; Cario, G; Schrappe, M; Eckert, C; von Stackelberg, A; Huang, J; Hameiri-Grossman, M; Avigad, S; Te Kronnie, G; Geron, I; Birger, Y; Rein, A; Zarfati, G; Fischer, U; Mukamel, Z; Stanulla, M; Biondi, A; Cazzaniga, G; Vetere, A; Wagner, B; Chen, Z; Chen, S; Tanay, A; Borkhardt, A; Izraeli, S
The histone deacetylase inhibitor givinostat (ITF2357) exhibits potent anti-tumor activity against CRLF2-rearranged BCP-ALL
2017 Savino, A; Sarno, J; Trentin, L; Vieri, M; Fazio, G; Bardini, M; Bugarin, C; Fossati, G; Davis, K; Gaipa, G; Izraeli, S; Meyer, L; Nolan, G; Biondi, A; Te Kronnie, G; Palmi, C; Cazzaniga, G
CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia
2016 Palmi, C; Savino, A; Silvestri, D; Bronzini, I; Cario, G; Paganin, M; Buldini, B; Galbiati, M; Muckenthaler, M; Bugarin, C; Mina, P; Nagel, S; Barisone, E; Casale, F; Locatelli, F; Nigro, L; Micalizzi, C; Parasole, R; Pession, A; Putti, M; Santoro, N; Testi, A; Ziino, O; Kulozik, A; Zimmermann, M; Schrappe, M; Villa, A; Gaipa, G; Basso, G; Biondi, A; Valsecchi, M; Stanulla, M; Conter, V; Kronnie, G; Cazzaniga, G
Prognostic value of rare IKZF1 deletion in childhood B-cell precursor acute lymphoblastic leukemia: An international collaborative study
2016 Boer, J; Van Der Veer, A; Rizopoulos, D; Fiocco, M; Sonneveld, E; De Groot Kruseman, H; Kuiper, R; Hoogerbrugge, P; Horstmann, M; Zaliova, M; Palmi, C; Trka, J; Fronkova, E; Emerenciano, M; Do Socorro Pombo De Oliveira, M; Mlynarski, W; Szczepanski, T; Nebral, K; Attarbaschi, A; Venn, N; Sutton, R; Schwab, C; Enshaei, A; Vora, A; Stanulla, M; Schrappe, M; Cazzaniga, G; Conter, V; Zimmermann, M; Moorman, A; Pieters, R; Den Boer, M
Fine tuning of surface CRLF2 expression and its associated signaling profile in childhood B-cell precursor acute lymphoblastic leukemia
2015 Bugarin, C; Sarno, J; Palmi, C; Savino, A; te Kronnie, G; Dworzak, M; Shumich, A; Buldini, B; Maglia, O; Sala, S; Bronzini, I; Bourquin, J; Mejstrikova, E; Hrusak, O; Luria, D; Basso, G; Izraeli, S; Biondi, A; Cazzaniga, G; Gaipa, G
Targeting of hyperactivated mTOR signaling in high-risk acute lymphoblastic leukemia in a pre-clinical model
2015 Hasan, M; Queudeville, M; Trentin, L; Eckhoff, S; Bronzini, I; Palmi, C; Barth, T; Cazzaniga, G; te Kronnie, G; Debatin, K; Meyer, L
Cytoskeletal Regulatory Gene Expression and Migratory Properties of B Cell Progenitors are Affected by the ETV6-RUNX1 Rearrangement
2014 Palmi, C; Fazio, G; Savino, A; Procter, J; Howell, L; Cazzaniga, V; Vieri, M; Longinotti, G; Brunati, I; Andre, V; Della Mina, P; Villa, A; Greaves, M; Biondi, A; D'Amico, G; Ford, A; Cazzaniga, G
PAX5 Fusion Genes Activate The STAT5 Signaling Pathway Through Lck Over-Expression
2013 Cazzaniga, V; Giordan, M; Bugarin, C; Palmi, C; Savino, A; Kronnie, G; Gaipa, G; Biondi, A; Fazio, G; Cazzaniga, G
PAX5/ETV6 alters the gene expression profile of precursor B cells with opposite dominant effect on endogenous PAX5
2013 Fazio, G; Cazzaniga, V; Palmi, C; Galbiati, M; Giordan, M; Te Kronnie, G; Rolink, A; Biondi, A; Cazzaniga, G
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